Rejection, Correction and Resubmission

A Guide for Authors

Introduction

Biography

The Outcomes Of a the First Submission

  • Rejection: Understanding reasons and planning next steps
  • Correction: Effective revision and response strategies
  • Resubmission: Making informed decisions

Unlikely your submission gets accepted at the first trial. If it does, did you send to a predatory journal?

PART 1: REJECTION

Reality Check: Rejection Statistics

High-Impact Medical Journals (2022-2025) 1

Journal Acceptance Rate
NEJM ~5%
JAMA 11% overall, 4% research
The Lancet ~5%
BMJ ~7% overall, 4% research
Nature Medicine <8%

Key Insight: Rejection is the norm, not the exception!

Acceptance Rates Across Journal Tiers

General Medical Journals 1

  • BMJ Open: 47% acceptance rate
  • Dove Medical Press: 76% rejection/withdrawal rate
  • Elsevier Analysis (2,371 journals): 32% average acceptance
  • Overall Reality: 62-90% rejection rates common

Common Rejection Reasons

Editorial Screening (20-30% of manuscripts)

1. Scope/Focus Misalignment

  • JAMA Internal Medicine: 78% rejected without review
  • Primary cause: outside journal scope

2. Lack of Novelty

  • Common fatal flaw
  • Work previously published with no novelty
  • Insufficient knowledge advancement (too superficial)

Editorial Screening (20-30% of manuscripts)

3. Poor Research Question

  • Among top rejection reasons
  • Unclear hypothesis
  • Data doesn’t answer question

Technical Rejection Reasons

Post-Peer-Review (45-70% of reviewed manuscripts)

  1. Methodological Flaws
    • Poor study design for example inadequate controls

    • Sample size inadequacy

    • Inappropriate statistical tests

    • Poor writing

Post-Peer-Review (45-70% of reviewed manuscripts)

  1. Statistical/Analytical Problems (40-60%)
    • Inappropriate analysis methods
    • Conclusions not supported by data
    • Poor writing
  2. Writing Quality/Language (15-25%)
    • Poor English/grammar

Discipline-Specific Patterns

Medical Specialty Rejection Rates

Post-Rejection Action Plan

Immediate Response Strategy (Days 1-7)

  1. Emotional Management
    • Take 2-7 day cooling-off period
    • Avoid immediate emotional responses
  2. Systematic Review Analysis
    • Read rejection letter carefully
    • Categorize feedback systematically
    • Determine revision potential
  3. Success Statistics
    • 76% rejected manuscripts published elsewhere <2 years
    • 70-89% eventual publication rate

Post-Rejection Success Strategies

Decision Framework (Week 1-2)

Option 1: Same Journal

  • 50% acceptance rate for invited revisions
  • Only if editor shows genuine interest

Option 2: Alternative Journal

  • 75-83% eventual publication success
  • Target appropriate scope
  • Slightly lower impact factor

Decision Framework (Week 1-2)

Long-term Success Factors

  • Pre-submission preparation
    • take adequate time
    • do not rush
    • revise and revise and revise
  • Collaborative approach
    • expert in the field
    • expert in the methods
    • expert in the analysis
  • Use journal selection tools
    • general journals
    • specific field journals
    • article processing fee

PART 2: CORRECTION

Understanding Revision Categories

Success Rates by Decision Type

Decision Type Acceptance Rate Timeline
Minor Revision 91.5-94.7% 5 days - 4 weeks
Major Revision 40.0-55.2% 10 days - 3 months
Provisional Accept 98% (“will”) / 90% (“may”) Variable
Reject & Resubmit ~50% No fixed deadline

Point-by-Point Response Strategy

Essential Structure Components

  1. Opening Summary: Brief overview of major changes
  2. Systematic Organization: Address each reviewer separately
  3. Comment-Response Format: Clear labeling
  4. Location References: Specific page, paragraph, line numbers

Response Template Structure

Dear Dr. [Editor Name],

We thank you and the reviewers for comprehensive feedback on 
manuscript "[Title]" (MS#[Number]).

## Major Revisions Summary:
- Re-analyzed data using appropriate statistical methods
- Expanded discussion of limitations
- Clarified methodology in response to reviewer concerns

## Detailed Responses:

### Reviewer 1:
**Comment 1:** [Exact reviewer text]

**Response:** We appreciate this observation. We have [specific 
action taken]. The revised text appears on page X, lines Y-Z...

Advanced Response Techniques

Addressing Methodology Concerns

Example Response

Comment R2.3: “Statistical analysis approach seems inappropriate.”

Response: We appreciate this observation. After biostatistician consultation, we agree and re-analyzed using linear mixed models per Smith et al. (2023). New analysis in revised Table 2 (page 8), discussed in Results (page 12, lines 15-28). This strengthened conclusions by accounting for repeated measures.

Handling Disagreements Professionally

Scope Limitations Example

Professional Disagreement

Comment R1.5: “Authors should include long-term outcomes.”

Response: We acknowledge the importance of long-term data. However, this extends beyond current study scope designed as a 6-month pilot study. We have added this as a limitation (page 16, lines 8-12) and suggested it as important future research direction.

Publisher-Specific Requirements

Major Publishers

  • Different fonts/colors for comments vs responses
  • Include manuscript tracking number
  • Separate “clean” and “tracked changes” versions
  • Address editor comments first
  • Journal-specific templates when provided
  • Formal letter formatting
  • Consistent citation style
  • Word count change statements
  • Label “COMMENT” (bold), “RESPONSE” (regular)
  • Journal-specific submission systems
  • Detailed change descriptions

Medical Journal Standards

ICMJE Guidelines Compliance

  • Authorship criteria: substantial contributions
  • Conflict of interest disclosure
  • Data sharing for clinical trials
  • Uniform manuscript preparation

ICMJE Guidelines Compliance

Clinical Trial Requirements

  • Registration number in abstract
  • CONSORT checklist compliance
  • Protocol as supplementary material
  • Patient flow diagram

Quality Control Checklist

✅ Do:

  • Have co-authors review
  • Cross-reference all changes
  • Verify page/line accuracy
  • Address every comment
  • Maintain professional tone

❌ Avoid:

  • Defensive tone
  • Incomplete responses
  • Inaccurate references
  • Unrequested changes
  • Ignoring editor comments

Optimal Revision Timeline

gantt
    title Revision Process Timeline
    dateFormat  YYYY-MM-DD
    section Initial Review
    Review & Planning           :2024-01-01, 7d
    section Major Changes
    Detailed Planning          :2024-01-08, 14d
    Implementation             :2024-01-22, 21d
    section Finalization
    Response Letter            :2024-02-12, 14d
    Peer Review                :2024-02-26, 7d
    Final Submission           :2024-03-05, 1d

PART 3: RESUBMISSION

Resubmission Decision Framework

Primary Decision Factors

  1. Type of Editorial Decision
    • Fixed deadline = effectively major revision ✅
    • No fixed deadline = true rejection with invitation ⚠️
    • Outright rejection = do NOT resubmit ❌
  2. Scope of Required Changes
    • Minor: Technical corrections ✅
    • Major: Additional analyses ⚠️
    • Fundamental: Complete overhaul ❌

Primary Decision Factors

  1. Reviewer Feedback Quality
    • Constructive, specific = favorable ✅
    • Fundamental concerns = alternative journal ⚠️

Risk Assessment Matrix

Success Probability Tiers

Probability Indicators Action
High (>70%) Minor revision, constructive feedback Resubmit same journal
Moderate (40-70%) Major revision with guidance Consider carefully
Low (<40%) Outright rejection, fundamental issues Try different journal

Same Journal vs. Different Journal

Same journal

1. Advantages

  • Editorial continuity
  • Established investment
  • Same reviewers understand
  • No restart needed

2. Success Rates

  • 80% eventual publication
  • 25.3% original research acceptance
  • 71% per submission (assoc. professors)

Same Journal vs. Different Journal

Different Journal

1. Indicate when

  • Scope mismatch indicated
  • Fundamental disagreement
  • Resources insufficient
  • Better IF match elsewhere

2. Strategic Considerations:

  • Disclosure requirements
  • Ethical transparency
  • Transfer services available

Publisher Resubmission Policies

Major Publishers

  • Allows resubmissions with disclosure
  • Cite previous submission in cover letter
  • Justification required
  • Accept from other journals
  • Disclose submission history
  • Manuscript transfer services
  • Format-free submission (350+ journals)
  • Transfer desk services
  • Clear preprint policies

Timeline Optimization

Journal-Specific Requirements

Journal Minor Revision Major Revision
J Med Libr Assoc 1 month 2 months
Med Decision Making - 3 months
AJR - 128.6 ± 83.8 days

Strategic Timing

  • Faster = demonstrates commitment
  • Delays = suggests low priority
  • Extensions: request early (1 week notice)

Success Factors Analysis

Factors Correlated with Higher Success

  • Academic rank: Associate professors highest
  • Systematic response: Address all comments
  • Prompt resubmission: Maintain enthusiasm
  • Clear improvement: Show enhancement
  • Professional communication: Collaborative tone

Common Failure Factors

What NOT to Do

Process Errors:

  • Ignoring reviewer suggestions
  • Unchanged manuscripts
  • Excessive delays
  • Poor communication

Content Errors:

  • Inadequate methodology fixes
  • Overstated conclusions
  • Missing limitations
  • Inconsistent terminology

Manuscript Transfer Services

Publisher Tools

  • Taylor & Francis: Article Transfer Service
    • Seamless transfer with review history
    • No resubmission fees
  • Springer Nature: Transfer desk
    • Review report portability
    • Editorial board overlap
  • Journal Selection Tools:

RESOURCES & TOOLS

Essential Publisher Resources

  • Author Hub: https://www.springernature.com/gp/authors
  • LaTeX and Word templates
  • AI-powered journal matching
  • Professional editing services
  • Author Services: https://authorservices.taylorandfrancis.com/
  • Format-free submission (350+ journals)
  • Unified submission portal
  • Article transfer service
  • Author Hub: https://www.elsevier.com/researcher/author
  • Researcher Academy (free e-learning)
  • Editorial Manager system
  • Language editing services

Medical Journal Resources

High-Impact Journals

NEJM

  • Rigorous accuracy checking
  • Digital image requirements
  • AI disclosure mandatory

JAMA

  • ICMJE compliance
  • Numbered references
  • Author statements

BMJ

  • Open peer review
  • Structured abstracts
  • Patient consent required

Professional Editing Services

Editage

Website: https://www.editage.com/

  • Three editing levels
  • 500,000+ researchers served
  • 365-day unlimited re-editing
  • Subject-matter experts

American Journal Experts (AJE)

Website: https://www.aje.com/

  • Native English editors
  • AI-enhanced tools
  • Springer Nature partnership
  • 100% satisfaction guarantee

Free Resources

Essential Tools

  1. PubMed Central: https://pmc.ncbi.nlm.nih.gov/
    • Submission documentation
    • NIH Public Access Policy
    • Technical requirements
  2. ORCID ID: Required by all major publishers
    • Unique researcher identifier
    • Streamlined submissions
  3. Reporting Standards:
    • CONSORT (clinical trials)
    • STROBE (observational)
    • PRISMA (systematic reviews)
    • CARE (case reports)

Quality Assurance Checklist

Pre-Submission Review

Content:

Technical:

Success Metrics & Benchmarks

Performance Tracking

Revision Type Target Success Timeline
Minor 91.5-94.7% 2-4 weeks
Major 40.0-55.2% 1-3 months
Reject & Resubmit ~50% Prompt preferred

Track Your Performance

  • Document all outcomes
  • Note reviewer feedback themes
  • Monitor time-to-acceptance
  • Analyze success/failure patterns

Advanced Strategies

Positioning for Top-Tier Journals

Key Success Factors:

  1. Clinical Significance: Clear patient impact
  2. Methodological Rigor: Robust design
  3. Novel Contributions: Beyond existing knowledge
  4. Broad Appeal: International relevance

Pre-Submission Strategies:

  • Editorial contact for borderline fit
  • Conference presentations
  • International collaborations
  • Media readiness

Common Mistakes to Avoid

Critical Errors

Methodological:

  • Inadequate sample size
  • Inappropriate statistics
  • Missing controls
  • Poor randomization

Presentation:

  • Overstated conclusions
  • Inadequate limitations
  • Poor figure design
  • Inconsistent terminology

Process:

  • Wrong journal scope
  • Ignoring formatting
  • Inadequate responses
  • Poor resubmission timing

SUMMARIES

Essential Success Principles

  1. Normalize Rejection
    • 62-90% rejection rates are common
    • Even quality research gets rejected
  2. Persistence Pays
    • 70-90% manuscripts eventually publish
    • Strategic approach crucial
  3. Systematic Approach
    • Evidence-based revision strategies
    • Significantly improve success
  4. Professional Communication
    • Respectful, collaborative tone
    • Throughout entire process

Immediate Action Steps

Today

This Week

This Month Action Plan

Essential Tasks

  1. Develop Pre-Submission Checklist
    • Content, technical, ethical review
  2. Practice Response Writing
    • Point-by-point format
    • Professional tone
  3. Build Support Network
    • Peer reviewers
    • Mentors
    • Statistical consultants
  4. Plan Data Management
    • Repository selection
    • Sharing strategy

For Epidemiology & Public Health Researchers

Discipline-Specific Recommendations

  • Follow STROBE guidelines religiously
  • Emphasize population health impact
  • Collaborate with biostatisticians early
  • Position within broader public health context

Success Mindset

  • Treat rejection as learning opportunity
  • Invest time in thorough preparation
  • Build systematic processes
  • Maintain professional persistence

Remember

Final Thoughts

Most successful researchers have faced multiple rejections.

The key is:

  1. Learning from each experience
  2. Applying evidence-based strategies
  3. Improving submission success over time
  4. Never giving up on quality research

References & Further Reading

Key Publications

  1. Wong, GLH. (2019). Tips for Responding to Reviewers’ Comments. Gut and Liver, 13(1), 7-10. DOI: 10.5009/gnl18361

  2. Noble, WS. (2017). Ten simple rules for writing a response to reviewers. PLOS Computational Biology, 13(10). DOI: 10.1371/journal.pcbi.1005730

  3. Provenzale, JM. (2010). Revising a manuscript: ten principles to guide success. AJR, 195(6), W382-W387. DOI: 10.2214/AJR.10.5553

  4. Springer Nature Common Rejection Reasons: https://www.springernature.com/gp/authors/campaigns/common-rejection-reasons

  5. Taylor & Francis Author Services: https://authorservices.taylorandfrancis.com/

  6. ICMJE Recommendations: https://www.icmje.org/recommendations/

Thank You!

Questions?

For More Information:

  • Springer Nature: https://www.springernature.com/gp/authors
  • Taylor & Francis: https://authorservices.taylorandfrancis.com/
  • Elsevier: https://www.elsevier.com/researcher/author
  • PubMed Central: https://pmc.ncbi.nlm.nih.gov/

Good luck with your manuscript submissions!

** Acknowledgement: I used Claude Sonnet 4.5 with Extended Thinking for creating the contents for the slide decks. You may find links for the content here

Connect with me on LinkedIn for collaboration and training opportunities.